Ahmadi Okay, Roshan-Milani S, Asgharzadeh F, Pourjabali M, Fard AA. In vitro and in vivo pretreatment with selenium mitigates tetrahydrocannabinol-induced testicular cell apoptosis: the function of AKT and p53 pathways. Biol Hint Elem Res. 2021;199(6):2278–87.
Al Shoyaib A, Archie SR, Karamyan VT. Intraperitoneal route of drug administration: ought to it’s utilized in experimental animal research? Pharm Res. 2019;37(1):12.
Altinok A, Coskun ZM, Karaoglu Okay, Bolkent S, Akkan AG, Ozyazgan S. Delta9-tetrahydrocannabinol remedy improved endothelium-dependent leisure on streptozotocin/nicotinamide-induced diabetic rat aorta. Acta Physiol Hung. 2015;102(1):51–9.
Banerjee BN, Sofia RD, Erikson D, Ivins NJ. Toxicity of delta9 -tetrahydrocannabinol (THC) administered subcutaneously for 13 days to feminine rabbits. J Toxicol Environ Well being. 1976;1(5):769–76.
Beydogan AB, Coskun ZM, Bolkent S. The protecting results of delta(9) -tetrahydrocannabinol towards irritation and oxidative stress in rat liver with fructose-induced hyperinsulinemia. J Pharm Pharmacol. 2019;71(3):408–16.
Borgen LA, Davis WM. Automobile and route of administration as parameters affecting operant behavioral results of 9 -tetrahydrocannabinol. J Pharm Sci. 1973;62(3):479–80.
Calik MW, Carley DW. Results of cannabinoid agonists and antagonists on sleep and inhaling Sprague-Dawley rats. Sleep. 2017;40(9):zsx112.
Craft RM, Wakley AA, Tsutsui KT, Laggart JD. Intercourse variations in cannabinoid 1 vs. cannabinoid 2 receptor-selective antagonism of antinociception produced by delta9-tetrahydrocannabinol and CP55,940 within the rat. J Pharmacol Exp Ther. 2012;340(3):787–800.
Dajani EZ, Larsen KR, Taylor J, Dajani NE, Shahwan TG, Neeleman SD, et al. 1’,1’-Dimethylheptyl-delta-8-tetrahydrocannabinol-11-oic acid: a novel, orally efficient cannabinoid with analgesic and anti inflammatory properties. J Pharmacol Exp Ther. 1999;291(1):31–8.
Fried PA. Cross-tolerance between inhaled hashish and intraperitoneal injections of delta9-THC. Pharmacol Biochem Behav. 1976;4(6):635–8.
Grotenhermen F. Pharmacokinetics and pharmacodynamics of cannabinoids. Clin Pharmacokinet. 2003;42(4):327–60.
Harte LC, Dow-Edwards D. Sexually dimorphic alterations in locomotion and reversal studying after adolescent tetrahydrocannabinol publicity within the rat. Neurotoxicol Teratol. 2010;32(5):515–24.
Hlozek T, Uttl L, Kaderabek L, Balikova M, Lhotkova E, Horsley RR, et al. Pharmacokinetic and behavioural profile of THC, CBD, and THC+CBD mixture after pulmonary, oral, and subcutaneous administration in rats and affirmation of conversion in vivo of CBD to THC. Eur Neuropsychopharmacol. 2017;27(12):1223–37.
Huestis MA. Human cannabinoid pharmacokinetics. Chem Biodivers. 2007;4(8):1770–804.
Kamali-Sarvestani A, Hoseini SE, Mehrabani D, Hashemi SS, Derakhshanfar A. Results in rats of adolescent publicity to Hashish sativa on emotional conduct and adipose tissue. Bratisl Lek Listy. 2020;121(4):297–301.
Klein M, de Quadros De Bortolli J, Guimaraes FS, Salum FG, Cherubini Okay, de Figueiredo MAZ. Results of cannabidiol, a Hashish sativa constituent, on oral wound therapeutic course of in rats: medical and histological analysis. Phytother Res. 2018;32(11):2275–81.
Lewis RE, Kunz AL, Bell RE. Error of intraperitoneal injections in rats. Lab Anim Care. 1966;16(6):505–9.
MacCallum CA, Russo EB. Sensible issues in medical hashish administration and dosing. Eur J Intern Med. 2018;49:12–9.
Madularu D, Yee JR, Kulkarni P, Ferris CF. System-specific exercise in response to delta(9) -tetrahydrocannabinol: a purposeful magnetic resonance imaging examine in awake male rats. Eur J Neurosci. 2017;46(12):2893–900.
Mahmoudinoodezh H, Telukutla SR, Bhangu SK, Bachari A, Cavalieri F, Mantri N. The transdermal supply of therapeutic cannabinoids. Pharmaceutics. 2022;14(2):438.
Marusich JA, Lefever TW, Antonazzo KR, Craft RM, Wiley JL. Analysis of intercourse variations in cannabinoid dependence. Drug Alcohol Rely. 2014;137:20–8.
Mechoulam R, Peters M, Murillo-Rodriguez E, Hanus LO. Cannabidiol–current advances. Chem Biodivers. 2007;4(8):1678–92.
Moore CF, Davis CM, Harvey EL, Taffe MA, Weerts EM. Appetitive, antinociceptive, and hypothermic results of vaped and injected delta-9-tetrahydrocannabinol (THC) in rats: publicity and dose-effect comparisons by pressure and intercourse. Pharmacol Biochem Behav. 2021;202:173116.
Moreira FA, Aguiar DC, Guimaraes FS. Anxiolytic-like impact of cannabidiol within the rat Vogel battle take a look at. Prog Neuropsychopharmacol Biol Psychiatry. 2006;30(8):1466–71.
Morton DB, Jennings M, Buckwell A, Ewbank R, Godfrey C, Holgate B, et al. Refining procedures for the administration of drugs. Report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement. British Veterinary Affiliation Animal Welfare Basis/Fund for the Substitute of Animals in Medical Experiments/Royal Society for the Prevention of Cruelty to Animals/Universities Federation for Animal Welfare. Lab Anim. 2001;35(1):1–41.
Nakano Y, Tajima M, Sugiyama E, Sato VH, Sato H. Improvement of a novel nano-emulsion formulation to enhance intestinal absorption of cannabidiol. Med Hashish Cannabinoids. 2019;2(1):35–42.
Nelson NG, Regulation WX, Weingarten MJ, Carnevale LN, Das A, Liang NC. Mixed (9)-tetrahydrocannabinol and average alcohol administration: results on ingestive behaviors in adolescent male rats. Psychopharmacology. 2019;236(2):671–84.
Nidadavolu P, Bilkei-Gorzo A, Kramer M, Schurmann B, Palmisano M, Beins EC, et al. Efficacy of delta(9) -tetrahydrocannabinol (THC) alone or together with a 1:1 ratio of cannabidiol (CBD) in reversing the spatial studying deficits in outdated mice. Entrance Growing older Neurosci. 2021;13:718850.
Ozaita A, Puighermanal E, Maldonado R. Regulation of PI3K/Akt/GSK-3 pathway by cannabinoids within the mind. J Neurochem. 2007;102(4):1105–14.
Pacula RL, Sensible R. Medical marijuana and marijuana legalization. Annu Rev Clin Psychol. 2017;13:397–419.
Paudel KS, Hammell DC, Agu RU, Valiveti S, Stinchcomb AL. Cannabidiol bioavailability after nasal and transdermal software: impact of permeation enhancers. Drug Dev Ind Pharm. 2010;36(9):1088–97.
Rock EM, Connolly C, Limebeer CL, Parker LA. Impact of mixed oral doses of delta(9)-tetrahydrocannabinol (THC) and cannabidiolic acid (CBDA) on acute and anticipatory nausea in rat fashions. Psychopharmacology. 2016;233(18):3353–60.
Schwotzer D, Kulpa J, Trexler Okay, Dye W, Jantzi J, Irshad H, et al. Pharmacokinetics of cannabidiol in Sprague-Dawley rats after oral and pulmonary administration. Hashish Cannabinoid Res. 2022;8(2):360–73. https://doi.org/10.1089/can.2022.0121.
Sheerin AH, Zhang X, Saucier DM, Corcoran ME. Selective antiepileptic results of N-palmitoylethanolamide, a putative endocannabinoid. Epilepsia. 2004;45(10):1184–8.
Sofia RD, Strasbaugh JE, Banerjee BN. Teratologic analysis of artificial delta 9-tetrahydrocannabinol in rabbits. Teratology. 1979;19(3):361–6.
Stinchcomb AL, Valiveti S, Hammell DC, Ramsey DR. Human pores and skin permeation of delta8-tetrahydrocannabinol, cannabidiol and cannabinol. J Pharm Pharmacol. 2004;56(3):291–7.
Thompson GR, Rosenkrantz H, Fleischman RW, Braude MC. Results of delta-9-tetrahydrocannabinol administered subcutaneously to rabbits for 28 days. Toxicology. 1975;4(1):41–51.
Turner PV, Brabb T, Pekow C, Vasbinder MA. Administration of drugs to laboratory animals: routes of administration and components to contemplate. J Am Assoc Lab Anim Sci. 2011;50(5):600–13.
Valvassori SS, Bavaresco DV, Scaini G, Varela RB, Streck EL, Chagas MH, et al. Acute and power administration of cannabidiol will increase mitochondrial complicated and creatine kinase exercise within the rat mind. Braz J Psychiatry. 2013;35(4):380–6.
Welch SP, Huffman JW, Lowe J. Differential blockade of the antinociceptive results of centrally administered cannabinoids by SR141716A. J Pharmacol Exp Ther. 1998;286(3):1301–8.
Wiley JL, Burston JJ. Intercourse variations in delta(9)-tetrahydrocannabinol metabolism and in vivo pharmacology following acute and repeated dosing in adolescent rats. Neurosci Lett. 2014;576:51–5.
Zatroch KK, Knight CG, Reimer JN, Pang DS. Refinement of intraperitoneal injection of sodium pentobarbital for euthanasia in laboratory rats (Rattus norvegicus). BMC Vet Res. 2017;13(1):60.
