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Effects of acute cannabis inhalation on reaction time, decision-making, and memory using a tablet-based application | Journal of Cannabis Research


  • Adam JJ. Gender differences in choice reaction time: evidence for differential strategies. Ergonomics. 1999;42(2):327–35.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Arkell TR, Spindle TR, Kevin RC, Vandrey R, McGregor IS. The failings of per se limits to detect cannabis-induced driving impairment: results from a simulated driving study. Traffic Inj Prev. 2021;22(2):102–7.

    Article 
    PubMed 

    Google Scholar
     

  • Asbridge M, Hayden JA, Cartwright JL. Acute cannabis consumption and motor vehicle collision risk: systematic review of observational studies and meta-analysis. BMJ. 2012;344:e536.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Bakhtiari R, Tomczak MV, Langor S, Scanlon JE, Granley A, Singhal A. Application of tablet-based cognitive tasks to predict unsafe drivers in older adults. Transp Res Interdiscip Perspect. 2020;4:100105.


    Google Scholar
     

  • Blough PM, Slavin LK. Reaction time assessments of gender differences in visual-spatial performance. Percept Psychophys. 1987;41(3):276–81.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Brooks-Russell A, Brown T, Friedman K, Wrobel J, Schwarz J, Dooley G, et al. Simulated driving performance among daily and occasional cannabis users. Accid Anal Prev. 2021;160:106326.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Broyd SJ, van Hell HH, Beale C, Yuecel M, Solowij N. Acute and chronic effects of cannabinoids on human cognition—a systematic review. Biol Psychiat. 2016b;79(7):557–68.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Burt TS, Brown TL, Milavetz G, McGehee DV. Mechanisms of cannabis impairment: implications for modeling driving performance. Forensic Sci Int. 2021;328:110902.

  • Chung T, Bae SW, Mun E, Suffoletto B, Nishiyama Y, Jang S, et al. Mobile assessment of acute effects of marijuana on cognitive functioning in young adults: observational study. JMIR mHealth and uHealth. 2020;8(3):e16240.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Cohen MJ, Rickles WH. Performance on a verbal learning task by subjects of heavy past marijuana usage. Psychopharmacologia. 1974;37(4):323–30.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Colizzi M, Bhattacharyya S. Cannabis use and the development of tolerance: a systematic review of human evidence. Neurosci Biobehav Rev. 2018;93:1–15.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Cooper ZD, Haney M. Comparison of subjective, pharmacokinetic, and physiological effects of marijuana smoked as joints and blunts. Drug Alcohol Depend. 2009;103(3):107–13.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • D’Souza DC, Braley G, Blaise R, Vendetti M, Oliver S, Pittman B, et al. Effects of haloperidol on the behavioral, subjective, cognitive, motor, and neuroendocrine effects of Δ-9-tetrahydrocannabinol in humans. Psychopharmacology. 2008;198(4):587–603.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Desrosiers NA, Ramaekers JG, Chauchard E, Gorelick DA, Huestis MA. Smoked cannabis’ psychomotor and neurocognitive effects in occasional and frequent smokers. J Anal Toxicol. 2015;39:251–61.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Downey LA, King R, Papafotiou K, Swann P, Ogden E, Boorman M, et al. Detecting impairment associated with cannabis with and without alcohol on the Standardized Field Sobriety Tests. Psychopharmacology. 2012;224(4):581–9.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • D’Souza DC, Ranganathan M, Braley G, Gueorguieva R, Zimolo Z, Cooper T, et al. Blunted psychoimimetic and amnestic effects of Δ9-tetrahydrocannabinol in frequent users of cannabis. Neuropsychopharmacology. 2008;33:2506–16.

    Article 

    Google Scholar
     

  • Figueiredo PR, Tolomeo S, Steele JD, Baldacchino A. Neurocognitive consequences of chronic cannabis use: a systematic review and meta-analysis. Neurosci Biobehav Rev. 2020;108:358–69.

    Article 
    PubMed 

    Google Scholar
     

  • Governors Highway Safety Association. Drug impaired driving: marijuana drug-impaired driving laws Washington, D.C.: Governors Highway Safety Association; 2023. Available from: https://www.ghsa.org/state-laws/issues/drug%20impaired%20driving.

  • Greenwald MK, Stitzer ML. Antinociceptive, subjective and behavioral effects of smoked marijuana in humans. Drug Alcohol Depend. 2000;59(3):261–75.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Hall W, Stjepanović D, Caulkins J, Lynskey M, Leung J, Campbell G, et al. Public health implications of legalising the production and sale of cannabis for medicinal and recreational use. The Lancet. 2019;394(10208):1580–90.

    Article 

    Google Scholar
     

  • Hart CL, Ilan AB, Gevins A, Gunderson EW, Role K, Colley J, et al. Neurophysiological and cognitive effects of smoked marijuana in frequent users. Pharmacol Biochem Behav. 2010;96(3):333–41.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Hartman RL, Brown TL, Milavetz G, Spurgin A, Gorelick DA, Gaffney G, et al. Controlled cannabis vaporizer administration: blood and plasma cannabinoids with and without alcohol. Clin Chem. 2015;61(6):850–69.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Hill AC, Laird AR, Robinson JL. Gender differences in working memory networks: a BrainMap meta-analysis. Biol Psychol. 2014;102:18–29.

    Article 
    PubMed 

    Google Scholar
     

  • Hirvonen J, Goodwin RS, Li CT, Terry GE, Zoghbi SS, Morse C, et al. Reversible and regionally selective downregulation of brain cannabinoid CB 1 receptors in chronic daily cannabis smokers. Mol Psychiatry. 2012;17(7):642.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Hunault CC, Mensinga TT, Böcker KB, Schipper CMA, Kruidenier M, Leenders ME, et al. Cognitive and psychomotor effects in males after smoking a combination of tobacco and cannabis containing up to 69 mg delta-9-tetrahydrocannabinol (THC). Psychopharmacology. 2009;204(1):85–94.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Ilan AB, Smith ME, Gevins A. Effects of marijuana on neurophysiological signals of working and episodic memory. Psychopharmacology. 2004;176(2):214–22.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Karoly HC, Milburn MA, Brooks-Russell A, Brown M, Streufert J, Bryan AD, et al. Effects of high-potency cannabis on psychomotor performance in frequent cannabis users. Cannabis Cannabinoid Res. 2022;7(1):107–15.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Lenth R. Package ‘lsmeans’. The American. Statistican. 2018;4:216–21.


    Google Scholar
     

  • Li MC, Brady JE, DiMaggio CJ, Lusardi AR, Tzong KY, Li G. Marijuana use and motor vehicle crashes. Epidemiol Rev. 2011;34(1):65–72.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • McCartney D, Arkell TR, Irwin C, McGregor IS. Determining the magnitude and duration of acute Δ9-tetrahydrocannabinol (Δ9-THC)-induced driving and cognitive impairment: a systematic and meta-analytic review. Neurosci Biobehav Rev. 2021;126:175–93.

  • McCartney D, Arkell TR, Irwin C, Kevin RC, McGregor IS. Are blood and oral fluid Δ9-tetrahydrocannabinol (THC) and metabolite concentrations related to impairment? A meta-regression analysis. Neurosci Biobehav Rev. 2022;134:104433.

  • MPG Consulting. 2019 Regulated Marijuana market update. Denver, CO: MPG Consulting; 2020.


    Google Scholar
     

  • National Highway Traffic Safety Administration. DWI Detection and Standardized Field Sobriety Test (SFST) Resources: U.S. Department of Transportation; 2023. Available from: https://www.nhtsa.gov/dwi-detection-and-standardized-field-sobriety-test-sfst-resources.

  • Pal R, Mendelson J, Clavier O, Baggott MJ, Coyle J, Galloway GP. Development and testing of a smartphone-based cognitive/neuropsychological evaluation system for substance abusers. J Psychoactive Drugs. 2016;48(4):288–94.

    Article 
    PubMed 

    Google Scholar
     

  • Papafotiou K, Carter JD, Stough C. An evaluation of the sensitivity of the Standardised Field Sobriety Tests (SFSTs) to detect impairment due to marijuana intoxication. Psychopharmacology. 2005;180(1):107–14.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • R Core Team. R: A language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing; 2013.


    Google Scholar
     

  • Ramaekers JG, Kauert G, van Ruitenbeek P, Theunissen EL, Schneider E, Moeller MR. High-potency marijuana impairs executive function and inhibitory motor control. Neuropsychopharmacology. 2006;31(10):2296–303.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Ramaekers JG, Kauert G, Theunissen EL, Toennes SW, Moeller MR. Neurocognitive performance during acute THC intoxication in heavy and occasional cannabis users. J Psychopharmacol. 2009;23(3):266–77.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Ramaekers JG, Theunissen EL, De Brouwer M, Toennes SW, Moeller MR, Kauert G. Tolerance and cross-tolerance to neurocognitive effects of THC and alcohol in heavy cannabis users. Psychopharmacology. 2011;214(2):391–401.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Ramaekers JG, Mason NL, Theunissen EL. Blunted highs: pharmacodynamic and behavioral models of cannabis tolerance. Eur Neuropsychopharmacol. 2020;36:191–205.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Ranganathan M, D’Souza DC. The acute effects of cannabinoids on memory in humans: a review. Psychopharmacology. 2006;188(4):425–44.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Rickles WH, Cohen MJ, Whitaker CA, McIntyre KE. Marijuana induced state-dependent verbal learning. Psychopharmacologia. 1973;30:349–54.

    Article 
    PubMed 

    Google Scholar
     

  • Rogeberg O. A meta-analysis of the crash risk of cannabis-positive drivers in culpability studies—avoiding interpretational bias. Acc Anal Prev. 2019;123:69–78.

    Article 

    Google Scholar
     

  • Schoeler T, Bhattacharyya S. The effect of cannabis use on memory function: an update. Subst Abuse Rehabil. 2013;4:11–27.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • Scott D, Atkin AE, Granley A, Singhal A. The utility of cognitive testing to predict real world commercial driving risk. Transp Res Interdiscip Perspect. 2023;18:100783.


    Google Scholar
     

  • Spindle TR, Martin EL, Grabenauer M, Woodward T, Milburn MA, Vandrey R. Assessment of cognitive and psychomotor impairment, subjective effects, and blood THC concentrations following acute administration of oral and vaporized cannabis. J Psychopharmacol. 2021;35(7):786–803.

  • Vadhan NP, Hart CL, van Gorp WG, Gunderson EW, Haney M, Foltin RW. Acute effects of smoked marijuana on decision making, as assessed by a modified gambling task, in experienced marijuana users. J Clin Exp Neuropsychol. 2007;29(4):357–64.

    Article 
    PubMed 

    Google Scholar
     

  • Van Wel JHP, Kuypers KPC, Theunissen EL, Toennes SW, Spronk DB, Verkes RJ, et al. Single doses of THC and cocaine decrease proficiency of impulse control in heavy cannabis users. Br J Pharmacol. 2013;170(7):1410–20.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Wood E, Brooks-Russell A, Drum P. Delays in DUI blood testing: Impact on cannabis DUI assessments. Traffic Inj Prev. 2016;17:105–8.

    Article 
    PubMed 

    Google Scholar
     

  • Wurz GT, DeGregorio MW. Indeterminacy of cannabis impairment and∆ 9-tetrahydrocannabinol (∆ 9-THC) levels in blood and breath. Sci Rep. 2022;12(1):1–11.

    Article 

    Google Scholar
     

  • Zhang H, Guo Y, Yuan W, Li K. On the importance of working memory in the driving safety field: a systematic review. Accid Anal Prev. 2023;187:107071.

    Article 
    PubMed 

    Google Scholar
     

  • Zhornitsky S, Pelletier J, Assaf R, Giroux S, Chiang-shan RL, Potvin S. Acute effects of partial CB1 receptor agonists on cognition–a meta-analysis of human studies. Prog Neuropsychopharmacol Biol Psychiatry. 2021;104:110063.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Dr. Jen Chalmers
    Dr. Jen Chalmers
    Dr. Jen Chalmers is an accomplished writer and cannabis enthusiast. With a Ph.D. in Botany and years of experience as a researcher, she brings a scientific perspective to her captivating articles on cannabis news, recipes, and the fascinating world of psychedelics.

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